For Khaya Senegalensis ( Australian Mahogany ) Bark Extract

نویسنده

  • BOTANICAL NAME
چکیده

The bitter tasting bark is used for a variety of medical purposes. An extract of the bark of Khaya senegalensis is commonly used in African traditional medicine for pain and inflammation, against fever caused by malaria, stomach complaints and headaches. It is widely used in the treatment of fever, malaria, to cure skin rashes, wounds, mucous diarrhea, as an anti-microbial agent in venereal diseases or many other abnormalities. It is also used as an anti-helminthic and as a taeniacide (tapeworm remedy) in West Africa. In Senegal, this plant is used against fever, to treat fatigue, and to treat malaria. Decoctions or macerations of the bark is the most common preparations used in the treatment of syphilis, vaginal discharge, leprosy and small pox, most likely because of its purgative properties. Syphilis and leprosy are also treated externally using leaf extracts. The gum from the plant has traditionally been used to treat dysentery, headache and menstrual pain (Sanogo, 1999).

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Potency of Aqueous Stem Bark Extract of Khaya Senegalensis against Liver Diseases in Rats

In order to assess the potency of aqueous stem bark extract of Khaya senegalensis (KS) against liver diseases, serum aspartate transaminase (AST), alanine transaminase (ALT) and alkaline phosphatase (ALP) were assayed in rats treated with two (2) different doses of the extract after the induction of liver damage in the rats using carbon tetrachloride, CCl4. The rats treated with a daily dose of...

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Chemopreventive effects of Khaya senegalensis bark extract on human colorectal cancer.

An extract of the bark of Khaya senegalensis is commonly used in African traditional medicine for pain and inflammation. Khaya senegalensis bark extract (KSBE) was hypothesized to contain inhibitors of the cyclooxygenase-2 (COX-2) gene and to be useful in the prevention and treatment of colorectal cancer. The diphenyl-2-picrylhydrazyl (DPPH)- free radical activity and the total phenolic content...

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Increased liver alkaline phosphatase and aminotransferase activities following administration of ethanolic extract of Khaya senegalensis stem bark to rats

The effect of daily, oral administration of ethanolic extract of Khaya senegalensis stem bark (2mg/kg body weight) for 18days on the alkaline phosphatase, aspartate and alanine aminotransferase activities of rat liver and serum were investigated. Compared with the control, the activities of liver alkaline phosphatase (ALP), alanine aminotransferase (ALT) and aspartate aminotransferase (AST) inc...

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Effect of Aqueous Stem Bark Extract of Khaya senegalensis on Some Biochemical, Haematological, and Histopathological Parameters of Rats

The subchronic effect of aqueous stem bark extract of Khaya senegalensis on some biochemical, haematological, and histopathological parameters of rats was investigated. The rats were divided into six groups of five rats per group. Groups I to VI were administered graded doses of 0, 400, 800, 1200, 1600, and 2000 mg/kg bw, respectively. The result of study revealed that administration of the Kha...

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تاریخ انتشار 2016